Seminars in Radiation Oncology
Volume 20, Issue 4 , Pages 217-222, October 2010

DNA Repair Targeting and Radiotherapy: A Focus on the Therapeutic Ratio

  • John Thoms, MD, MSc

      Affiliations

    • Departments of Radiation Oncology and Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
    • Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    • ,
  • Robert G. Bristow, MD, PhD

      Affiliations

    • Departments of Radiation Oncology and Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
    • Radiation Medicine Program, Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada
    • Prostate Cancer Research Program, Campbell Family Cancer Research Institute, Ontario Cancer Institute, Toronto, Ontario, Canada
    • Corresponding Author InformationAddress reprint requests to Robert G. Bristow, MD, PhD, Radiation Medicine Program, Princess Margaret Hospital, 610 University Avenue Toronto, ON M5G 2M9, Canada

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 Supported by operating grants from Prostate Cancer Canada, the Terry Fox Research Institute, the Ontario Institute for Cancer Research, the US Army DOD Prostate Program, an infrastructure grant from the Canadian Foundation for Innovation grant to the STTARR Innovation Facility, and in part by the Ontario Ministry of Health and Long-Term Care.

 The views expressed do not necessarily reflect those of the OMOHLTC. RGB is a Canadian Cancer Society Research scientist and JT is a CFCRI-OCI Prostate Cancer Fellow.

PII: S1053-4296(10)00045-7

doi:10.1016/j.semradonc.2010.06.003

Seminars in Radiation Oncology
Volume 20, Issue 4 , Pages 217-222, October 2010

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