Seminars in Radiation Oncology
Volume 19, Issue 4 , Pages 244-255, October 2009

Radiation Techniques and Toxicities for Locally Advanced Breast Cancer

  • Meena S. Moran, MD

      Affiliations

    • Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT
    • Corresponding Author InformationAddress reprint requests to Meena S. Moran, MD, Yale University School of Medicine, 333 Cedar Street, PO Box 208040, New Haven, CT 06520-8040
  • ,
  • Bruce G. Haffty, MD

      Affiliations

    • Department of Radiation Oncology, UMDNJ-Robert Wood Johnson School of Medicine, New Brunswick, NJ
    • The Cancer Institute of New Jersey, New Brunswick, NJ

Radiation therapy is used in the management of locally advanced breast cancer in the postmastectomy or neoadjuvant chemotherapy and breast-conservation setting to improve local-regional control and survival. Using modern-day technology, the therapeutic ratio has increased and the potential morbidity has decreased. This article reviews the technical aspects of radiation therapy for locally advanced breast cancer with emphasis on 3-dimensional radiotherapy techniques and discusses potential toxicities and how to reduce them.

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PII: S1053-4296(09)00044-7

doi:10.1016/j.semradonc.2009.05.007

Seminars in Radiation Oncology
Volume 19, Issue 4 , Pages 244-255, October 2009