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Seminars in Radiation Oncology
Volume 19, Issue 2
, Pages 96-105
, April 2009
Cancer Stem Cells and Tumor Response to Therapy: Current Problems and Future Prospects
References
- Concomitant boost radiotherapy schedules in the treatment of carcinoma of the oropharynx and nasopharynx. Int J Radiat Oncol Biol Phys. 1990;19:1339–1345
- A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: First report of RTOG 9003. Int J Radiat Oncol Biol Phys. 2000;48:7–16
- Continuous, hyperfractionated, accelerated radiotherapy (CHART) versus conventional radiotherapy in non-small cell lung cancer: Mature data from the randomized multicentre trial. Radiother Oncol. 1999;52:137–148
- High-dose intensity modulated radiation therapy for prostate cancer: Early toxicity and biochemical outcome in 772 patients. Int J Radiat Oncol Biol Phys. 2002;53:1111–1116
- . Intensity-modulated therapy: A clinical perspective (Introduction). Semin Radiat Oncol. 2002;197–198
- . Cancer stem cells. N Engl J Med. 2006;355:1253–1261
- Stem cells and cancer. Semin Cancer Biol. 2007;17:191–203
- . Context, tissue plasticity, and cancer: Are tumor stem cells also regulated by the microenvironment?. Cancer Cells. 2005;7:17–23
- . No place like home: Anatomy and function of the stem cell niche. Nat Rev Mol Cell Biol. 2008;9:11–21
- . Stem cells and niches: Mechanisms that promote stem cell maintenance throughout life. Cell. 2008;132:598–611
- . Radiation and the microenvironment—Tumorigenesis and therapy. Nat Rev Cancer. 2005;5:867–875
- . Exploring the role of cancer stem cells in radioresistance. Nat Rev Cancer. 2008;8:545–554
- . Cancer stem cells: An old idea—A paradigm shift. Cancer Res. 2006;66:1883–1890
- . Identifying cancer stem cells in solid tumors: Case not proven. Cancer Res. 2006;66:1891–1896
- . Tumor physiology and drug resistance. Cancer Metastasis Rev. 2001;20:123–132
- . The hazard of accelerated tumors clonogen repopulation during radiotherapy. Acta Oncol. 1988;27:131–146
- . Radiological and clinical implications of the stem cell concept in human malignancy. In: Cory JG, Szentivany A editor. Cancer Biology and Therapeutics. New York, NY: Plenum Publishing; 1987;p. 65–76
- . A critical appraisal of the “human tumor stem-cell assay. ” N Engl J Med. 1983;308:129–134
- . The proportion of stem cells in murine tumors. Int J Radiat Oncol Biol Phys. 1989;16:513–518
- Repopulation during fractionated radiotherapy: Much has been learned, even more is open. Int J Radiat Biol. 2003;79:465–467
- . The fuzzy math of solid tumor stem cells: A perspective. Cancer Res. 2007;67:8985–8988
- . Is tumor growth sustained by rare cancer stem cells or dominant clones?. Cancer Res. 2008;68:4018–4021
- . Effect of lethally damaged tumor cells upon the development of admixed viable cells. J Natl Cancer Inst. 1958;20:1157–1186
- . The effect of lethally irradiated cells on the transplantability of murine tumours. Br J Cancer. 1973;28:123–135
- Retardation of tumor growth in mice caused by radiation-induced injury of tumor bed stoma: Dependency on tumor type. Cancer Res. 1986;46:712–727
- . Conditioning of tissues for metastasis formation by radiation and cytotoxic drugs. In: Nicholson GL, Milas L editor. Cancer Invasion and Metastasis: Biologic and Therapeutic Aspects. New York, NY: Raven Press; 1984;p. 321–336
- . Normal stem cells and cancer stem cells: The niche matters. Cancer Res. 2006;66:4553–4557
- . Roots and stems: Stem cells in cancer. Nat Med. 2006;12:296–300
- . Epithelial stem cells: Turning over new leaves. Cell. 2007;128:445–458
- . Textbook of Radiotherapy. Philadelphia, PA: Lea & Febiger; 1980;
- Changes in TCD50 as a measure of clonogen doubling time in irradiated and unirradiated tumors. Int J Radiat Oncol Biol Phys. 1991;21:1195–1202
- Dynamics of tumor cell clonogen repopulation in a murine sarcoma treated with cyclophosphamide. Radiother Oncol. 1994;30:247–253
- Accelerated repopulation during fractionated irradiation of a murine ovarian carcinoma: Downregulation of apoptosis as a possible mechanism. Int J Radiat Oncol Biol Phys. 1996;35:951–962
- . The role of altered fractionation in head and neck cancers. Semin Radiat Oncol. 1992;2:18–194
- A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature. 2007;445:106–110
- . Selection and extended growth of murine epidermal stem cells in culture. Exp Cell Res. 1998;244:184–195
- Isolation and functional properties of murine hematopoietic stem cells that are replicating in Vivo. J Exp Med. 1996;193:1797–1806
- . Cancer stem cell biology: from leukemia to solid tumors. Curr Opin Cell Biol. 2004;16:708–712
- Prospective identification of tumorigenic breat cancer cells. PNAS. 2003;100:3983–3988
- . Diverse mechanisms regulate stem cell self-renewal. Curr Opin Cell Biol. 2004;16:700–707
- Identification of a cancer stem cell in human brain tumors. Cancer Res. 2003;63:5821–5828
- Cancerous stem cells can arise from pediatric brain tumors. Proc Natl Acad Sci U S A. 2003;100:15178–15183
- Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med. 2006;12:1167–1174
- . Organizing cell renewal in the intestine: Stem cells, signals and combinatorial control. Nat Rev Genet. 2006;7:349–359
- . Leukaemia: Niche retreats for stem cells. Nature. 2006;444:827–828
- . Tissue repair and stem cell renewal in carcinogenesis. Nature. 2004;432:324–331
- Maintenance of neuroepithelial progenitor cells by delta-notch signaling in the embryonic chick retina. Curr Biol. 1997;7:661–670
- Osteoblastic cells regulate the hematopoietic stem cell niche. Nature. 2003;435:841–846
- β-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell. 2002;111:251–263
- The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell. 2002;111:241–250
- Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nat Neurosci. 2003;6:21–27
- . An empty drosophila stem cell niche reactivates the proliferation of ectopic cells. Proc Natl Acad Sci U S A. 2003;100:4633–4638
- . The hedgehog signaling pathway in cancer. Clin Cancer Res. 2006;12:5924–5928
- . Radiobiology for the Radiologist. ed 5. New York, NY: Lippincott Williams & Wilkins; 2000;
- . Hypoxia-inducible factors, stem cells, and cancer. Cell. 2007;129:465–472
- Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006;444:756–760
- . Cancer stem cells in radiation resistance. Cancer Res. 2007;67:8980–8984
- PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo. Genes Dev. 2008;22:436–448
- . Tumor hypoxia in cancer therapy. Methods Enzymol. 2007;435:297–321
- Erythropoietin biology in cancer. Clin Cancer Res. 2006;12:332–339
- . Tumor angiogenesis: Therapeutic implications. N Engl J Med. 1971;285:1182–1186
- . Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell. 1996;86:353–364
- . Angiogenesis as a therapeutic target. Nature. 2005;438:967–974
- . Antiangiogenic therapy: A universal chemosensitization strategy for cancer?. Science. 2006;312:1171–1175
- Potentiation of cytotoxic therapies by TNP-470 and minocycline in mice bearing EMT-6 mammary carcinoma. Breast Cancer Res Treat. 1995;36:227–236
- . Preclinical studies of the combination of angiogenic inhibitors with cytotoxic agents. Invest N Drugs. 1997;15:39–48
- . Normalizing tumor vasculature with antiangiogenic therapy: A new paradigm for combination therapy. Nat Med. 2001;7:987–989
- Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: Role of oxygenation, angiopoitin-1, and matrix metalloproteinases. Cancer Cells. 2004;6:553–563
- Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment. Clin Cancer Res. 2005;11:743–750
- Trimodel cancer treatment: Beneficial effects of combined antiangiogenesis, radiation, and chemotherapy. Cancer Res. 2005;65:3643–3655
- Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med. 1998;338:1798–1804
- Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer. N Engl J Med. 1999;340:1137–1143
- Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer. J Clin Oncol. 1999;17:2692–2699
- . Should randomized clinical trials be required for proton radiotherapy?. J Clin Oncol. 2008;26:175–176
- . Targeting tyrosine kinases in cancer: The second wave. Science. 2006;312:1175–1178
- . Targeting checkpoint kinase 1 in cancer therapeutics. Clin Cancer Res. 2007;13:1955–1960
- Dynamics of chronic myeloid leukaemia. Nature. 2005;435:1267–1270
- . Epidermal growth factor receptor and its inhibition in radiotherapy: In-vivo findings. Int J Radiat Biol. 2003;79:539–545
- Signal transduction and cellular radiation responses. Radiat Res. 2000;153:245–257
- Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation. Oncogene. 1997;15:1191–1197
- In-vivo enhancement of tumor radio response by C225 antiepidermal growth factor receptor antibody. Clin Cancer Res. 2000;6:701–708
- . Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: Inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis. Clin Cancer Res. 2000;6:2166–2174
- . Blockade of receptors for growth factors: An anticancer therapy (The fourth annual Joseph H Burchenal American Association for Cancer Research Clinical Research award lecture). Clin Cancer Res. 2000;6:747–753
- C225 antiepidermal growth factor receptor antibody enhances tumor radio curability. Int Radiat Oncol J Biol Phys. 2001;51:474–477
- Targeted therapies and radiation for the treatment of head and neck cancer: Are we making progress?. Semin Radiat Oncol. 2004;14:139–152
- Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck. N Engl J Med. 2006;354:567–578
- Decreased repopulation as well as increased reoxygenation contribute to the improvement in local control after targeting of the EGFR by C225 during fractionated irradiation. Radiother Oncol. 2005;76:162–167
- Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase. J Biol Chem. 2005;280:31182–31189
- . An oncogene-induced DNA damage model for cancer development. Science. 2008;319:1352–1355
- Relationship between cyclin D1 expression and poor radio response of murine carcinomas. Int J Radiat Oncol Biol Phys. 2002;52:514–521
- Flavopiridol increases therapeutic ratio of radiotherapy by preferentially enhancing tumor radio response. Int J Radiat Oncol Biol Phys. 2004;59:1181–1189
- Flavopiridol, a cyclin-dependent kinase inhibitor, enhances radiosensitivity of ovarian carcinoma cells. Cancer Res. 2003;63:3263–3267
- . Mechanisms of action of flavopiridol (Crit). Rev Oncol. 2001;38:139–170
- Targeting the hedgehog pathway to mitigate treatment resistance. Cell Cycle. 2007;6:1826–1830
- Polymeric retinoid prodrug PG-4HPR enhances the radiation response of lung cancer. Oncol Rep. 2007;18:645–651
- . Experimental evaluation of tumor bed effect of C3H mouse mammary carcinoma and for C3H mouse fibrosarcoma. Radiat Res. 1970;45:41–49
- . The tumor bed effect: Dependence of tumor take, growth rate, and metastasis on the time interval between irradiation and tumor cell transplantation. Int J Radiat Oncol Biol Phys. 1987;13:379–383
- . Tumor bed effect in murine tumors: Relationship to tumor take and tumor macrophage content. Radiat Res. 1990;123:232–236
- Tumor bed irradiation enhances sensitivity of A431 tumor xenografts to C225 anti-EGFR antibody. Proc Am Assoc Cancer Res. 2008;49:abstr. No. 1318
- Drug resistance and the solid tumor microenvironment. J Natl Cancer Inst. 2007;99:1441–1154
- Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335–2342
- . Role of vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol. 2005;23:1011–1127
- Angiostatin: A circulating endothelial cell inhibitor that suppresses angiogenesis and tumor growth. Cold Spring Harb Symp Quant Biol. 1994;59:471–482
- Angiostatin induces and sustains dormancy of human primary tumors in mice. Nat Med. 1996;2:689–692
- Importance of maintenance therapy in C225-induced enhancement of tumor control by fractionated radiation. Int J Radiat Oncol Biol Phys. 2007;67:568–572
- . Enhancing radiotherapy with cyclooxygenase-2 enzyme inhibitors: A Rational Advance?. J Natl Cancer Inst. 2003;95:1440–1452
- Dependence of indomethacin-induced potentiation of murine tumor radio response on tumor host immunocompetence. Cancer Res. 1990;50:4473–4477
- . Experimental evaluation of potential anticancer agents XIII: On the criteria and kinetics associated with “curability” of experimental leukemia. Cancer Chemother Rep. 1964;35:1–111
Supported by NCI Grants CA-06294, CA-106451, CA-103830, CA-16672, DE 13,157, DAMD 17-02-1-0706, and DAMD 17-1-1-0689.
PII: S1053-4296(08)00080-5
doi: 10.1016/j.semradonc.2008.11.004
© 2009 Elsevier Inc. All rights reserved.
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Seminars in Radiation Oncology
Volume 19, Issue 2
, Pages 96-105
, April 2009
