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Seminars in Radiation Oncology
Volume 19, Issue 2
, Pages 87-95
, April 2009
Radiosensitivity of Cancer-Initiating Cells and Normal Stem Cells (or what the Heisenberg Uncertainly Principle has to do with Biology)
References
- . Applying the principles of stem-cell biology to cancer. Nat Rev Cancer. 2003;3:895–902
- . Radiation, the ideal cytotoxic aged for studying the cell biology of tissues such as the small intestine. Rad Res. 2004;161:123–136
- . Steepness of the radiation dose-response curve for dose-per-fraction escalation keeping the number of fractions fixed. Acta Oncol. 2005;44:825–828
- . Preventing or reducing late side effects of radiation therapy: Radiobiology meets molecular pathology. Nat Rev Cancer. 2006;6:702–713
- . Evaluation of early and late toxicities in chemoradiation trials. J Clin Oncol. 2007;25:4096–4103
- . The radioresponsiveness of human tumours and the initial slope of the cell survival curve. Radiother Oncol. 1984;2:317–323
- . Comparison between in vitro radiosensitivity and in vivo radio response in murine tumor cell lines (II: In vivo radio response following fractionated treatment and in vitro/in-vivo correlations). Int J Radiat Oncol Biol Phys. 1990;18:331–345
- Estimation of clonogenic cell fraction in primary cultures derived from human squamous cell carcinomas. Int J Radiat Oncol Biol Phys. 1991;21:661–665
- . Invited review: Intrinsic radiosensitivity as a predictor of patient response to radiotherapy. Br J Radiol. 1995;68:827–837
- . Exploring the role of cancer stem cells in radioresistance. Nat Rev Cancer. 2008;8:545–554
- Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 2006;444:756–760
- . The proportion of stem cells in murine tumors. Int J Radiat Oncol Biol Phys. 1989;16:513–518
- In-vitro intrinsic radiation sensitivity of glioblastoma multiforme. Int J Radiat Oncol Biol Phys. 1992;23:55–62
- Cellular radiosensitivity of primary head and neck squamous cell carcinomas and local tumor control. Int J Radiat Oncol Biol Phys. 1990;18:1283–1286
- In-vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. Genes Dev. 2003;17:1253–1270
- Let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell. 2007;131:1109–1123
- Generation of a functional mammary gland from a single stem cell. Nature. 2006;439:84–88
- Purification and unique properties of mammary epithelial stem cells. Nature. 2006;439:993–997
- Isolation and characterization of functional mammary gland stem cells. Cell Prolif. 2003;36(suppl 1):17–32
- SCA-1(Pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol. 2002;245:42–56
- A distinct “side population” of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci U S A. 2004;101:14228–14233
- . Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line. Proc Natl Acad Sci U S A. 2004;101:781–786
- Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo. Proc Natl Acad Sci U S A. 2002;99:12339–12344
- Wnt/beta-catenin mediates radiation resistance of mouse mammary progenitor cells. Proc Natl Acad Sci U S A. 2007;104:618–623
- . The response of CD24(−/low)/CD44+ breast cancer-initiating cells to radiation. J Natl Cancer Inst. 2006;98:1777–1785
- Potential identity of multi-potential cancer stem-like subpopulation after radiation of cultured brain glioma. BMC Neurosci. 2008;9:1–12
- PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo. Genes Dev. 2008;22:436–448
- Identification of CD133− positie radioresistant cells in atypical teratoid/rhabdoid tumor. PLoS ONE. 2008;3:1–13
- Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A. 2003;100:3983–3988
- . Resistance of tumor cells to chemo- and radiotherapy modulated by the three-dimensional architecture of solid tumors and spheroids. Methods Cell Biol. 2001;64:211–233
- Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. Cancer Res. 2006;66:1526–1535
- Identification of tumor-initiating cells in a p53-null mouse model of breast cancer. Cancer Res. 2008;68:4674–4682
- . Neural stem cells and neurospheres—Re-evaluating the relationship. Nat Methods. 2005;2:333–336
- . Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science. 1992;255:1707–1710
- Identification of human brain tumour initiating cells. Nature. 2004;432:396–401
- Identification of a putative instestinal stem cell and early lineage marker; Musashi-1. Differentiation. 2003;71:28–41
- Knockdown of RNA binding protein Musashi-1 leads to tumor regression in Vivo. Gastroenterology. 2008;134:1448–1458
- Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironment. Cancer Res. 2007;67:11687–11695
- A correlation between residual DNA double-Strand breaks and clonogenic measurements of radiosensitivity in fibroblasts from preradiotherapy cervix cancer patients. Int J Radiat Oncol Biol Phys. 1997;39:1137–1144
- Phosphorylated histone H2AX in relation to cell survival in tumor cells and xenografts exposed to single and fractionated doses of X-rays. Radiother Oncol. 2006;80:223–229
- DNA double-strand break repair and radiation response in human tumour primary cultures. Int J Radiat Biol. 1994;66:279–285
- Homologous recombination and prostate cancer: A model for novel DNA repair targets and therapies. Radiother Oncol. 2007;83:220–230
- . Biomarkers for DNA DSB inhibitors and radiotherapy clinical trials. Cancer Metastasis Rev. 2008;27:445–458
- . DNA damage responses: Mechanisms and roles in human disease: 2007 G (HA Clowes memorial award lecture). Mol Cancer Res. 2008;6:517–524
- . Survival of the fittest: Cancer stem cells in therapeutic resistance and angiogenesis. J Clin Oncol. 2008;26:2839–2845
- BRCA1 regulates human mammary stem/progenitor cell fate. Proc Natl Acad Sci U S A. 2008;105:1680–1685
- . DNA repair is crucial for maintaining hematopoietic stem cell function. DNA Repair (Amst). 2008;7:523–529
- DNA repair is limiting for haematopoietic stem cells during ageing. Nature. 2007;447:686–690
- Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age. Nature. 2007;447:725–729
- . Tumor hypoxia, DNA repair and prostate cancer progression: New targets and new therapies (Future). Oncol. 2007;3:329–341
- . Hypoxia and metabolism (Hypoxia, DNA repair and genetic instability). Nat Rev Cancer. 2008;8:180–192
- Hypoxia causes Down-regulation of mismatch repair system and genomic instability in stem cells. Stem Cells. 2008;
- The sensitivity of human mesenchymal stem cells to ionizing radiation. Int J Radiat Oncol Biol Phys. 2006;66:244–253
- . DNA repair in murine embryonic stem cells and differentiated cells. Exp Cell Res. 2008;314:1929–1936
- Human embryonic stem cells have enhanced repair of multiple forms of DNA damage. Stem Cells. 2008;
- Mouse but not human embryonic stem cells are deficient in rejoining of ionizing radiation-induced DNA double-strand breaks. DNA Repair (Amst). 2008;7:1471–1483
- . Experimental concepts for toxicity prevention and tissue restoration after central nervous system irradiation. Radiol Oncol. 2007;2:23
- Rescue of salivary gland function after stem cell transplantation in irradiated glands. PLos ONE. 2008;3(4):e2063
- Mobilization of bone marrow stem cells by granulocyte colony-stimulating factor ameliorates radiation-induced damage to salivary glands. Clin Cancer Res. 2006;12(6):1804–1812
- . Clinical biomarkers and imaging for radiotherapy-induced cell death. Cancer Metastasis Rev. 2008;27:471–480
- . Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133− cells, and the CD133+ sector is enlarged by hypoxia. Int J Radiat Oncol Biol Phys. 2007;67:1–5
- Fluctuation of the SP/non-SP phenotype in the C6 glioma cell line. FEBS Lett. 2007;581:1435–1440
- Detection of migration of locally implanted AC133+ stem cells by cellular magnetic resonance imaging with histological findings. FASEB J. 2008;
- Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line. J Cell Sci. 2007;120:468–477
PII: S1053-4296(08)00079-9
doi: 10.1016/j.semradonc.2008.11.003
© 2009 Elsevier Inc. All rights reserved.
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Seminars in Radiation Oncology
Volume 19, Issue 2
, Pages 87-95
, April 2009
